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Chapter 45

Hypothesis

Hypotheses and suppositions; conjecture in science and reasoning; testing assumptions.

263 passages · 81 principal · Covers the 49 volumes of primary texts

Hypothesis is the act of supposing: laying down something not yet known to be true so that reasoning can proceed from it, and so that its consequences can be compared with what is found. The idea covers the deliberate postulate of the geometer, the tentative guess of the naturalist, the conditional reasoning of the moralist about origins no witness saw, and the emendations of the textual critic. It belongs among the great ideas of these books because nearly every inquiry they record moves by supposition. When Plato’s Socrates says he assumes the strongest principle he can find and accepts as true whatever agrees with it1, he names a procedure that Kelvin, many centuries later, calls simply unavoidable2. Between these two lie questions that are still open. What entitles a supposition to belief? How is it tried? When should it be abandoned?

The first question is whether reasoning can do without hypotheses at all. The authors who answer most firmly are the ones who use them most skilfully. Harvey, though he prides himself on demonstration rather than the conjecture of others3, assumes quantities of blood merely as a ground for reasoning, and notes that his conclusion holds whatever figures are supposed4. His circular motion was first conceived as what must be the case if the blood is to return from arteries to veins5. Descartes explains why he calls certain propositions hypotheses even while claiming to deduce them from first truths. Causes and effects, he says, lend each other support, and this is no vicious circle6. Locke recommends the Copernican motion of the planets to the learner as the simplest hypothesis and the likeliest true7. Yet he advises reading the philosophical systems to learn their hypotheses, not in the expectation of satisfying knowledge8. Lyell allows that the assumed course of nature may be supplied hypothetically, but only if it is kept consistent with probability and with analogy to what is observed9. Carlyle draws a moral line here: what is unproven should stay on the hypothetical side of the barrier until it has truly been acquired10.

A second use of hypothesis arises where facts cannot decide. Rousseau, inquiring into the origin of inequality, sets the facts aside. He calls his reasonings hypothetical and conditional, meant to illustrate the nature of things, much as naturalists frame systems of the world’s formation11. He declines to trace man’s bodily origin through comparative anatomy, judging that only vague conjectures are possible there, and so supposes man always formed as now12. He admits that his whole account rests on conjecture, defends it as the most probable and the only available means of finding the truth13, and adds that such hypotheses cannot be overthrown, since they cannot be given the certainty of facts14. Kant’s case differs in kind. For him freedom is a necessary hypothesis of reason in any being conscious of a will15. Practical reason must presuppose it, and it is consistent with physical necessity16. Rousseau’s supposition is necessary because evidence is lacking. Kant’s is necessary because action is impossible without it. Neither is meant to be tested as Harvey’s was, and this marks one boundary of the idea.

Most authors who conjecture take care to say so. Pliny offers several explanations of a fountain’s rhythm, from air currents to a hidden reservoir, and leaves his friend to judge17. Newton presents his suspicion about the forces of particles explicitly as a conjecture18. Franklin found that by offering his observations as conjectures rather than dogmas he was under no obligation to defend them19. Darwin’s journal is full of guesses labelled as such. He suggests that phosphorescence may come from decaying organic particles20 and that circling vultures signal prey to one another21, and he concedes that his speculations on rates of elevation are vague22. In the Origin he proposes a duck-like ancestor only as not incredible23, and he declines to speak with certainty about the origin of an instinct24. Helmholtz hedges his account of ice granules25, and Geikie calls his figures tentative and open to correction26. Milton places a different kind of modesty in Raphael’s mouth. Astronomers’ devices to “save appearances” are mocked27, and a string of “what if” suppositions about sun, earth and other worlds is left undecided28. Milton’s caution is reverent where the naturalists’ is methodical.

The more consequential question is how a supposition is put to trial. Copernicus treats the earth’s motion as a postulate to be tried, on the principle that a false hypothesis would not produce verified results29. He faults earlier astronomers for hypotheses that fitted the phenomena without corresponding to them30. Descartes adds that where several deductions are possible, crucial experiments yielding different results must decide among them31. Voltaire describes Newton conjecturing that gravity reaches the moon and then checking the supposition against measurement32. Faraday stages the method before his audience: steam, hydrogen or some other gas, each tested in turn33. Helmholtz devises an experiment to test Thomson’s explanation of the plasticity of ice34. He confirms a theoretical prediction quantitatively35 and recalls how Davy’s experiment with ice disposed of the latent-heat account of friction36. Even Dante’s Paradise contains such a trial, when the poet’s conjecture about dense and rare bodies is examined and found false37.

Prediction gives the trial its sharpest form. Darwin states plainly what would destroy his theory38, and he observes that contrary results on species and varieties would have been fatal39. He reasons from selection to how bees must build, then tests the reasoning with wax and vermilion. The bees stop excavating where planes intersect and leave flat walls40,41, results that also correct Huber42. He predicted slight revolving movements in non-climbing plants, which Fritz Müller later found43. The coral-reef theory is tested the same way. Fringing reefs should mark stationary or rising land44, dead and submerged reefs should exist45, and the coloured map should sort reef types by the movements of the land46. Darwin warns that his inference about volcanoes was hazardous until their absence from subsiding areas confirmed it47. Pasteur lays a wager that fruit cells will act as yeast in carbonic acid gas, and tests it48. He holds that theoretical ideas, however improbable at first, are confirmed when new facts bear them out49. He even predicts a patient’s recovery from his cultures50.

Not every theory can be tested crucially, and a further criterion appears: the range of facts a theory explains. Burke defends a theory grounded in experiment as good for what it explains, even if it does not account for every poetic image51. Darwin makes this criterion the backbone of his case. A theory should be accepted if it explains large bodies of facts that are otherwise inexplicable52. He likens natural selection to the undulatory theory of light and to gravitation53. He contrasts it with a creation view that explains nothing54,55. Huxley, quoted in the volume, calls descent an unproven hypothesis, yet the only one physiology supports56. The criterion carries an obligation to face objections, and Darwin does so candidly. He admits difficulties that might be fatal57, judges most of them only apparent58, and concedes that the theory stands or falls with the imperfection of the geological record59. He argues that negative evidence from that record is nearly worthless60. Here a tension appears. Explaining gaps by supposition can resemble the ad hoc patching that other authors condemn, and Darwin seems aware of it when he asks for allowances for ignorance only within limits61.

Rival hypotheses are therefore weighed openly. Darwin rejects in turn the theories of atolls that rest on protective instinct, on submarine craters, and on Chamisso’s growth at the outer edge, because each ignores the problem of the foundation62. Subsidence alone solves it63, and it accounts besides for the form, grouping and alignment of atolls64. Lyell traces the prejudices that held geology back. Earlier geologists conjectured what might have been instead of studying present causes65. Violent catastrophes were invoked without restraint from analogy66, and the Woodwardian hypothesis crowded countless rare events into a few months67. His imagined subterranean philosopher shows how theories mirror the narrow range of phenomena their authors observe68. Darwin follows him in refusing sudden revolutions of climate to explain the frozen Siberian animals69 and the debacle proposed by catastrophist geologists70. He also judges Forbes’s land bridges insufficiently evidenced71. Kelvin turns the same weapon on the geologists themselves. Tidal evidence shows the earth as rigid as steel, not a thin shell over molten lava72,73, and he denies any right to assume interior fluidity74.

The sharpest polemics are directed at gratuitous hypotheses. Voltaire charges that Descartes left geometry to frame hypotheses, making philosophy an ingenious romance75, and that the vortex theory heaps hypothesis on hypothesis without establishing that its matter exists76. Pasteur condemns convenient theories that receive a new hypothesis whenever facts contradict them, as with Liebig and Fremy77. He calls Liebig’s contact-action obscure and gratuitous78 and Traube’s ferment imaginary79. He discards spontaneous generation and an independent virus until only the hypothesis that the vibrio itself is responsible remains80. Newcomb finds Struve’s extinction of light unsupported by facts81. Berkeley carries the critique into metaphysics. Hylas’s brain-traces are absurd because the brain is itself only an idea82. Hylas finally concedes that material substance was a groundless hypothesis83, while Philonous claims to frame no hypothesis at all, only plain belief in what the senses show84. Whether this disclaimer itself rests on a supposition is a question the dialogue raises without settling.

Good inquirers also correct their own suppositions. Darwin supposed the air at sea was moist until measurement proved the reverse85. He abandoned his belief that a plain had been deposited by the sea once pottery and relics pointed to an earthquake wave86. He gave up a simultaneous cooling of the whole world for Croll’s explanation87, and he revised a view after a reviewer’s argument88. In Helmholtz’s history of physics the caloric theory fitted many processes89 until heat generated by friction from no known source undermined it90. The kinetic theory then came forward as a probable account91. Kelvin, by contrast, holds the ether a reality of science, inferred from the vibrations of light92,93, and finds support for the speculative hypothesis of an elastic ether in wax that yields like pitch and yet is elastic94. In the medical writings, Jenner offers the origin of cow-pox from the horse as presumptive evidence and not proof95. He leaves his conjectures for experiment to decide96,97 and hopes they will direct others to closer inquiry98. Lister conjectures that decomposition in wounds can be prevented by killing the floating particles rather than shutting out the air99.

Outside natural science, hypothesis takes on other functions. Hume offers custom as the only hypothesis that explains inference from repeated instances100, and proposes to test his account of experimental reasoning on animals101. He grants that the religious hypothesis may explain visible phenomena, but he holds that it licenses no added facts102. Any further attribute ascribed to the Author of nature he calls mere conjecture103,104. Browne, on the other hand, values guardian angels as a hypothesis that resolves doubts ordinary philosophy cannot105. Lessing defends transmigration as an old hypothesis that is not laughable merely because it is old106. Mill’s father would treat the Manichaean theory as a mere hypothesis107. Emerson reports metaphysicians calling the astronomers’ impulse an unreasonable postulate that begs the question108.

History and criticism have their own discipline of conjecture. Herodotus offers his own conjecture that the sun lowers the Nile in winter109, and he judges the unseen by the evident when he compares the Nile with the Ister110. Johnson observes that editors indulge conjecture beyond warrant111. Conjectural criticism, he says, has no axiomatic system and yields at best one probable reading among many112, so it is harmless only if kept in the margin113. Macaulay tests the rival explanations of The Prince against Machiavelli’s other works and refutes them114. Emerson finds the theories of Stonehenge built on coincidences of names115. Freeman holds that the origins of the Aryans remain unprovable conjecture116, while he entertains alternative suppositions about them117. Renan distrusts hypotheses that are more ingenious than solid118. Bagehot admits his reading of a woman’s motives is mere hypothesis119. Washington warns that changes made on hypothesis invite perpetual change120. Darwin notes that travellers fill the gaps in their knowledge with superficial hypotheses121.

Across these texts there is wide agreement that supposition is indispensable and that it must be marked as supposition. There is also agreement that deduced consequences, crucial experiments and explanatory range are its proper trials. The disagreements lie elsewhere. Some suppositions can never meet a test: Rousseau’s origins, Kant’s freedom, Hume’s deity. Where these belong in knowledge remains unsettled. So does the line between legitimate auxiliary supposition and the ad hoc patching that Pasteur and Voltaire denounce, which explanatory power alone cannot draw.

Passages cited (121)
  1. Plato, Phaedo, Vol. 2, p. 92–93read · scan
  2. William Thomson, Lord Kelvin, The Tides, Vol. 30, p. 280–281read · scan
  3. William Harvey, On the Motion of the Heart and Blood in Animals, Vol. 38, p. 87–88read · scan
  4. William Harvey, On the Motion of the Heart and Blood in Animals, Vol. 38, p. 104read · scan
  5. William Harvey, On the Motion of the Heart and Blood in Animals, Vol. 38, p. 100–101read · scan
  6. René Descartes, Discourse on the Method of Rightly Conducting the Reason and Seeking the Truth in the Sciences, Vol. 34, p. 60read · scan
  7. John Locke, Some Thoughts Concerning Education, Vol. 37, p. 154–155read · scan
  8. John Locke, Some Thoughts Concerning Education, Vol. 37, p. 165read · scan
  9. Sir Charles Lyell, Uniformity in the Series of Past Changes in the Animate and Inanimate World, Vol. 38, p. 399read · scan
  10. Thomas Carlyle, Inaugural Address at Edinburgh, Vol. 25, p. 361read · scan
  11. Jean-Jacques Rousseau, A Discourse upon the Origin and the Foundation of the Inequality among Mankind, Vol. 34, p. 166–167read · scan
  12. Jean-Jacques Rousseau, A Discourse upon the Origin and the Foundation of the Inequality among Mankind, Vol. 34, p. 168read · scan
  13. Jean-Jacques Rousseau, A Discourse upon the Origin and the Foundation of the Inequality among Mankind, Vol. 34, p. 195–196read · scan
  14. Jean-Jacques Rousseau, A Discourse upon the Origin and the Foundation of the Inequality among Mankind, Vol. 34, p. 196read · scan
  15. Immanuel Kant, Fundamental Principles of the Metaphysic of Morals, Vol. 32, p. 369read · scan
  16. Immanuel Kant, Fundamental Principles of the Metaphysic of Morals, Vol. 32, p. 371read · scan
  17. Pliny the Younger, Letters of Pliny, Vol. 9, p. 259read · scan
  18. Sir Isaac Newton, Preface to the Philosophiae Naturalis Principia Mathematica, Vol. 39, p. 150–152read · scan
  19. Benjamin Franklin, His Autobiography, Vol. 1, p. 147–148read · scan
  20. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 168–169read · scan
  21. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 189–190read · scan
  22. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 374read · scan
  23. Charles Darwin, The Origin of Species, Vol. 11, p. 225–226read · scan
  24. Charles Darwin, The Origin of Species, Vol. 11, p. 267read · scan
  25. Hermann von Helmholtz, Ice and Glaciers, Vol. 30, p. 247–248read · scan
  26. Sir Archibald Geikie, Geographical Evolution, Vol. 30, p. 341–342read · scan
  27. John Milton, Paradise Lost, Vol. 4, p. 243read · scan
  28. John Milton, Paradise Lost, Vol. 4, p. 243–246read · scan
  29. Nicolaus Copernicus, Dedication of the Revolutions of the Heavenly Bodies, Vol. 39, p. 53–55read · scan
  30. Nicolaus Copernicus, Dedication of the Revolutions of the Heavenly Bodies, Vol. 39, p. 53read · scan
  31. René Descartes, Discourse on the Method of Rightly Conducting the Reason and Seeking the Truth in the Sciences, Vol. 34, p. 51read · scan
  32. Voltaire, Letters on the English, Vol. 34, p. 115read · scan
  33. Michael Faraday, The Chemical History of a Candle, Vol. 30, p. 131read · scan
  34. Hermann von Helmholtz, Ice and Glaciers, Vol. 30, p. 245–246read · scan
  35. Hermann von Helmholtz, Ice and Glaciers, Vol. 30, p. 232read · scan
  36. Hermann von Helmholtz, On the Conservation of Force, Vol. 30, p. 196–197read · scan
  37. Dante Alighieri, Paradise, Vol. 20, p. 289read · scan
  38. Charles Darwin, The Origin of Species, Vol. 11, p. 185read · scan
  39. Charles Darwin, The Origin of Species, Vol. 11, p. 67–68read · scan
  40. Charles Darwin, The Origin of Species, Vol. 11, p. 270read · scan
  41. Charles Darwin, The Origin of Species, Vol. 11, p. 271read · scan
  42. Charles Darwin, The Origin of Species, Vol. 11, p. 272read · scan
  43. Charles Darwin, The Origin of Species, Vol. 11, p. 241read · scan
  44. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 480read · scan
  45. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 481–482read · scan
  46. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 483read · scan
  47. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 483–484read · scan
  48. Louis Pasteur, The Physiological Theory of Fermentation, Vol. 38, p. 302–303read · scan
  49. Louis Pasteur, The Physiological Theory of Fermentation, Vol. 38, p. 298–299read · scan
  50. Louis Pasteur, On the Extension of the Germ Theory to the Etiology of Certain Common Diseases, Vol. 38, p. 380read · scan
  51. Edmund Burke, Preface to the Second Edition of On the Sublime and Beautiful, Vol. 24, p. 8read · scan
  52. Charles Darwin, The Origin of Species, Vol. 11, p. 182–183read · scan
  53. Charles Darwin, The Origin of Species, Vol. 11, p. 497read · scan
  54. Charles Darwin, The Origin of Species, Vol. 11, p. 153–154read · scan
  55. Charles Darwin, The Origin of Species, Vol. 11, p. 487read · scan
  56. Charles Darwin, The Origin of Species, Vol. 11, p. 17read · scan
  57. Charles Darwin, The Origin of Species, Vol. 11, p. 277–278read · scan
  58. Charles Darwin, The Origin of Species, Vol. 11, p. 169–170read · scan
  59. Charles Darwin, The Origin of Species, Vol. 11, p. 375–376read · scan
  60. Charles Darwin, The Origin of Species, Vol. 11, p. 339–340read · scan
  61. Charles Darwin, The Origin of Species, Vol. 11, p. 427–428read · scan
  62. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 470read · scan
  63. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 471–472read · scan
  64. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 477–478read · scan
  65. Sir Charles Lyell, Uniformity in the Series of Past Changes in the Animate and Inanimate World, Vol. 38, p. 415read · scan
  66. Sir Charles Lyell, Uniformity in the Series of Past Changes in the Animate and Inanimate World, Vol. 38, p. 416–417read · scan
  67. Sir Charles Lyell, Prejudices Which Have Retarded the Progress of Geology, Vol. 38, p. 390read · scan
  68. Sir Charles Lyell, Prejudices Which Have Retarded the Progress of Geology, Vol. 38, p. 395read · scan
  69. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 96read · scan
  70. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 185read · scan
  71. Charles Darwin, The Origin of Species, Vol. 11, p. 386read · scan
  72. William Thomson, Lord Kelvin, The Tides, Vol. 30, p. 299–301read · scan
  73. William Thomson, Lord Kelvin, The Tides, Vol. 30, p. 305read · scan
  74. William Thomson, Lord Kelvin, The Tides, Vol. 30, p. 305–307read · scan
  75. Voltaire, Letters on the English, Vol. 34, p. 112–113read · scan
  76. Voltaire, Letters on the English, Vol. 34, p. 113–114read · scan
  77. Louis Pasteur, The Physiological Theory of Fermentation, Vol. 38, p. 352–353read · scan
  78. Louis Pasteur, The Physiological Theory of Fermentation, Vol. 38, p. 353–354read · scan
  79. Louis Pasteur, The Physiological Theory of Fermentation, Vol. 38, p. 316read · scan
  80. Louis Pasteur, The Germ Theory and Its Applications to Medicine and Surgery, Vol. 38, p. 367read · scan
  81. Simon Newcomb, The Extent of the Universe, Vol. 30, p. 320read · scan
  82. George Berkeley, Three Dialogues Between Hylas and Philonous, Vol. 37, p. 229–230read · scan
  83. George Berkeley, Three Dialogues Between Hylas and Philonous, Vol. 37, p. 250read · scan
  84. George Berkeley, Three Dialogues Between Hylas and Philonous, Vol. 37, p. 250–251read · scan
  85. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 14read · scan
  86. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 373–374read · scan
  87. Charles Darwin, The Origin of Species, Vol. 11, p. 400–401read · scan
  88. Charles Darwin, The Origin of Species, Vol. 11, p. 97read · scan
  89. Hermann von Helmholtz, On the Conservation of Force, Vol. 30, p. 194read · scan
  90. Hermann von Helmholtz, On the Conservation of Force, Vol. 30, p. 195–196read · scan
  91. Hermann von Helmholtz, On the Conservation of Force, Vol. 30, p. 200read · scan
  92. William Thomson, Lord Kelvin, The Wave Theory of Light, Vol. 30, p. 264read · scan
  93. William Thomson, Lord Kelvin, The Wave Theory of Light, Vol. 30, p. 271–272read · scan
  94. William Thomson, Lord Kelvin, The Wave Theory of Light, Vol. 30, p. 272read · scan
  95. Edward Jenner, The Three Original Publications on Vaccination Against Smallpox, Vol. 38, p. 180–181read · scan
  96. Edward Jenner, The Three Original Publications on Vaccination Against Smallpox, Vol. 38, p. 186–187read · scan
  97. Edward Jenner, The Three Original Publications on Vaccination Against Smallpox, Vol. 38, p. 201–202read · scan
  98. Edward Jenner, The Three Original Publications on Vaccination Against Smallpox, Vol. 38, p. 171read · scan
  99. Joseph Lister, On the Antiseptic Principle of the Practice of Surgery, Vol. 38, p. 257read · scan
  100. David Hume, An Enquiry Concerning Human Understanding, Vol. 37, p. 321read · scan
  101. David Hume, An Enquiry Concerning Human Understanding, Vol. 37, p. 371read · scan
  102. David Hume, An Enquiry Concerning Human Understanding, Vol. 37, p. 398–399read · scan
  103. David Hume, An Enquiry Concerning Human Understanding, Vol. 37, p. 403read · scan
  104. David Hume, An Enquiry Concerning Human Understanding, Vol. 37, p. 400read · scan
  105. Sir Thomas Browne, Religio Medici, Vol. 3, p. 284read · scan
  106. Gotthold Ephraim Lessing, The Education of the Human Race, Vol. 32, p. 205–206read · scan
  107. John Stuart Mill, Autobiography, Vol. 25, p. 29read · scan
  108. Ralph Waldo Emerson, Nature, Vol. 5, p. 231read · scan
  109. Herodotus, An Account of Egypt, Vol. 33, p. 15–17read · scan
  110. Herodotus, An Account of Egypt, Vol. 33, p. 20read · scan
  111. Samuel Johnson, Preface to Shakespeare, Vol. 39, p. 233–234read · scan
  112. Samuel Johnson, Preface to Shakespeare, Vol. 39, p. 247read · scan
  113. Samuel Johnson, Preface to Shakespeare, Vol. 39, p. 246–247read · scan
  114. Thomas Babington Macaulay, Machiavelli, Vol. 27, p. 364read · scan
  115. Ralph Waldo Emerson, English Traits, Vol. 5, p. 456–457read · scan
  116. Edward Augustus Freeman, Race and Language, Vol. 28, p. 240read · scan
  117. Edward Augustus Freeman, Race and Language, Vol. 28, p. 240read · scan
  118. Ernest Renan, The Poetry of the Celtic Races, Vol. 32, p. 167read · scan
  119. Walter Bagehot, John Milton, Vol. 28, p. 180–182read · scan
  120. George Washington, Washington's Farewell Address, Vol. 43, p. 240read · scan
  121. Charles Darwin, The Voyage of the Beagle, Vol. 29, p. 507–508read · scan

Introductory essay written by Claude Opus 5.5 from the outline and the notes on every passage below; quotations are checked against this edition.

  1. 1The nature and uses of hypothesis
    1. 1aHypothesis as a necessary instrument of reasoning
    2. 1bHypothetical reasoning where facts cannot decide
    3. 1cConjecture offered modestly as conjecture
  2. 2Testing hypotheses by experiment and prediction
    1. 2aCrucial experiments and trials of a supposition
    2. 2bPredictions fulfilled or falsified
  3. 3The criterion of explanatory power
  4. 4Rival hypotheses weighed and rejected
    1. 4aRejection of unsupported or catastrophic theories
    2. 4bCriticism of gratuitous or ad hoc hypotheses
    3. 4cRevision of one's own hypothesis
  5. 5Particular hypotheses in natural science
    1. 5aDescent, species and the origin of life
    2. 5bCoral reefs, geology and earth history
    3. 5cHeat, light, ether and cosmic hypotheses
    4. 5dDisease, fermentation and medicine
  6. 6Hypothesis and conjecture in philosophy, religion and letters
    1. 6aMetaphysical and religious hypotheses
    2. 6bConjecture in history, criticism and everyday life

1.The nature and uses of hypothesis

1a.Hypothesis as a necessary instrument of reasoning

Plato, PhaedoVol. 2

William Harvey, On the Motion of the Heart and Blood in AnimalsVol. 38

René Descartes, Discourse on the Method of Rightly Conducting the Reason and Seeking the Truth in the SciencesVol. 34

John Locke, Some Thoughts Concerning EducationVol. 37

Thomas Carlyle, Inaugural Address at EdinburghVol. 25

Sir Charles Lyell, Uniformity in the Series of Past Changes in the Animate and Inanimate WorldVol. 38

William Thomson, Lord Kelvin, The TidesVol. 30

1b.Hypothetical reasoning where facts cannot decide

Jean-Jacques Rousseau, A Discourse upon the Origin and the Foundation of the Inequality among MankindVol. 34

Immanuel Kant, Fundamental Principles of the Metaphysic of MoralsVol. 32

1c.Conjecture offered modestly as conjecture

Pliny the Younger, Letters of PlinyVol. 9

William Harvey, On the Motion of the Heart and Blood in AnimalsVol. 38

Sir Isaac Newton, Preface to the Philosophiae Naturalis Principia MathematicaVol. 39

Benjamin Franklin, His AutobiographyVol. 1

Charles Darwin, The Origin of SpeciesVol. 11

Charles Darwin, The Voyage of the BeagleVol. 29

Hermann von Helmholtz, Ice and GlaciersVol. 30

Sir Archibald Geikie, Geographical EvolutionVol. 30

2.Testing hypotheses by experiment and prediction

2a.Crucial experiments and trials of a supposition

See also: Experience 9e

Dante Alighieri, ParadiseVol. 20

Nicolaus Copernicus, Dedication of the Revolutions of the Heavenly BodiesVol. 39

René Descartes, Discourse on the Method of Rightly Conducting the Reason and Seeking the Truth in the SciencesVol. 34

Voltaire, Letters on the EnglishVol. 34

Michael Faraday, The Chemical History of a CandleVol. 30

Charles Darwin, The Origin of SpeciesVol. 11

Charles Darwin, The Voyage of the BeagleVol. 29

Hermann von Helmholtz, On the Conservation of ForceVol. 30

Hermann von Helmholtz, Ice and GlaciersVol. 30

2b.Predictions fulfilled or falsified

Charles Darwin, The Origin of SpeciesVol. 11

Charles Darwin, The Voyage of the BeagleVol. 29

Hermann von Helmholtz, Ice and GlaciersVol. 30

Louis Pasteur, The Physiological Theory of FermentationVol. 38

Louis Pasteur, On the Extension of the Germ Theory to the Etiology of Certain Common DiseasesVol. 38

3.The criterion of explanatory power

See also: Geology 4b

Edmund Burke, Preface to the Second Edition of On the Sublime and BeautifulVol. 24

Charles Darwin, The Origin of SpeciesVol. 11

Charles Darwin, The Voyage of the BeagleVol. 29

4.Rival hypotheses weighed and rejected

Charles Darwin, The Origin of SpeciesVol. 11

Charles Darwin, The Voyage of the BeagleVol. 29

4a.Rejection of unsupported or catastrophic theories

See also: Geology 2b · Physics 6b

Sir Charles Lyell, Prejudices Which Have Retarded the Progress of GeologyVol. 38

Sir Charles Lyell, Uniformity in the Series of Past Changes in the Animate and Inanimate WorldVol. 38

Charles Darwin, The Origin of SpeciesVol. 11

Charles Darwin, The Voyage of the BeagleVol. 29

William Thomson, Lord Kelvin, The TidesVol. 30

4b.Criticism of gratuitous or ad hoc hypotheses

Nicolaus Copernicus, Dedication of the Revolutions of the Heavenly BodiesVol. 39

George Berkeley, Three Dialogues Between Hylas and PhilonousVol. 37

Voltaire, Letters on the EnglishVol. 34

Louis Pasteur, The Physiological Theory of FermentationVol. 38

Louis Pasteur, The Germ Theory and Its Applications to Medicine and SurgeryVol. 38

Simon Newcomb, The Extent of the UniverseVol. 30

4c.Revision of one's own hypothesis

Charles Darwin, The Origin of SpeciesVol. 11

Charles Darwin, The Voyage of the BeagleVol. 29

5.Particular hypotheses in natural science

5a.Descent, species and the origin of life

See also: Evolution 3a · Cause 9a

Charles Darwin, The Origin of SpeciesVol. 11

Charles Darwin, The Voyage of the BeagleVol. 29

5b.Coral reefs, geology and earth history

See also: Change 5a · Geology 6c · Science 3d · Cause 8b

Charles Darwin, The Origin of SpeciesVol. 11

Charles Darwin, The Voyage of the BeagleVol. 29

Sir Archibald Geikie, Geographical EvolutionVol. 30

5c.Heat, light, ether and cosmic hypotheses

See also: Physics 5b · Matter 1c

John Milton, Paradise LostVol. 4

Hermann von Helmholtz, On the Conservation of ForceVol. 30

William Thomson, Lord Kelvin, The Wave Theory of LightVol. 30

William Thomson, Lord Kelvin, The TidesVol. 30

Simon Newcomb, The Extent of the UniverseVol. 30

5d.Disease, fermentation and medicine

See also: Life and Death 1d · Medicine 9c · Cause 9b · Experience 9c

Edward Jenner, The Three Original Publications on Vaccination Against SmallpoxVol. 38

Louis Pasteur, The Physiological Theory of FermentationVol. 38

Louis Pasteur, On the Extension of the Germ Theory to the Etiology of Certain Common DiseasesVol. 38

Joseph Lister, On the Antiseptic Principle of the Practice of SurgeryVol. 38

6.Hypothesis and conjecture in philosophy, religion and letters

6a.Metaphysical and religious hypotheses

See also: Cause 2e · Nature 4d · God 1c

Sir Thomas Browne, Religio MediciVol. 3

John Milton, Paradise LostVol. 4

John Locke, Some Thoughts Concerning EducationVol. 37

George Berkeley, Three Dialogues Between Hylas and PhilonousVol. 37

David Hume, An Enquiry Concerning Human UnderstandingVol. 37

Gotthold Ephraim Lessing, The Education of the Human RaceVol. 32

Ralph Waldo Emerson, NatureVol. 5

John Stuart Mill, AutobiographyVol. 25

6b.Conjecture in history, criticism and everyday life

Herodotus, An Account of EgyptVol. 33

Sir Walter Raleigh, The Discovery of GuianaVol. 33

Molière, Tartuffe, or The HypocriteVol. 26

John Locke, Some Thoughts Concerning EducationVol. 37

Voltaire, Letters on the EnglishVol. 34

Samuel Johnson, Preface to ShakespeareVol. 39

Sydney Smith, Fallacies of Anti-ReformersVol. 27

George Washington, Washington's Farewell AddressVol. 43

Alessandro Manzoni, I Promessi Sposi (The Betrothed)Vol. 21

Thomas Carlyle, Sir Walter ScottVol. 25

Thomas Babington Macaulay, MachiavelliVol. 27

Ralph Waldo Emerson, English TraitsVol. 5

Henry Wadsworth Longfellow, PoemsVol. 42

Charles Darwin, The Voyage of the BeagleVol. 29

Richard Henry Dana, Jr., Two Years Before the MastVol. 23

Edward Augustus Freeman, Race and LanguageVol. 28

Ernest Renan, The Poetry of the Celtic RacesVol. 32

Walter Bagehot, John MiltonVol. 28

See also: Cause, Geology, Evolution, Science, Physics, Experience